Nine of the top-10 most fuel efficient vehicles in the U.S. are hybrids. The agency, which sets guidelines and gives estimated fuel costs and mileage standards each year in its Fuel Economy Guide, released the following EPA ratings for 2010 models:
1. Toyota Prius, 51 mpg city/48 mpg highway; 2. Ford Fusion/Mercury Milan, 41/36; 3. Honda Civic Hybrid, 40/45; 4. Honda Insight (hybrid), 40/43; 5. Lexus HS250h (hybrid), 35/34; 6. Nissan Altima Hybrid, 35/33; 7. Ford Escape Hybrid FWD, Mazda Tribute Hybrid 2WD, Mercury Mariner Hybrid FWD, 34/31; 8. Smart fortwo Cabriolet (automatic) Smart fortwo Coupe (automatic), 33/41; 9. Toyota Camry Hybrid, 33/34 10. Lexus RX450h (hybrid, 2WD), 32/28.
Article Last Updated: March 27, 2026.
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A sports, travel and business journalist for more than 45 years, James has written the new car review column The Weekly Driver since 2004.
In addition to founding this site in 2004, James writes a Sunday automotive column for The San Jose Mercury and East Bay Times in Walnut Creek, Calif., and monthly auto review and wellness columns for Gulfshore Business, a magazine in Southwest Florida.
An author and contributor to many newspapers, magazines and online publications, co-hosted The Weekly Driver Podcast from 2017 to 2024.